Antioxidant Tripeptide
Glutathione
The body's master antioxidant tripeptide, central to redox and detoxification research.
Overview
Glutathione (GSH) is a tripeptide of glutamate, cysteine, and glycine and the most abundant intracellular antioxidant. Its reactive thiol group neutralizes reactive oxygen species and regenerates other antioxidants, making the GSH/GSSG ratio a standard marker of cellular redox state.
Research interest centers on glutathione’s roles in detoxification, immune-cell function, and protection against oxidative stress. It is studied both as an endogenous defense system and as a supplemented compound in cell and animal models.
Specification
| 0 | Sequence, u03b3-Glu-Cys-Gly |
|---|---|
| 1 | Molecular formula, Cu2081u2080Hu2081u2087Nu2083Ou2086S |
| 2 | Molecular weight, 307.32 g/mol |
| 3 | CAS number, 70-18-8 |
| 4 | Synonyms, GSH, L-Glutathione (reduced) |
Research areas
- Antioxidant defense
- Detoxification pathways
- Redox signaling
- Immune-cell research
References
- 1. Glutathione: Overview of its protective roles, measurement, and biosynthesis Molecular Aspects of Medicine 2009 Forman HJ, Zhang H, Rinna A
- 2. Glutathione synthesis Biochimica et Biophysica Acta 2013 Lu SC
- 3. Glutathione! Integrative Medicine (Encinitas) 2014 Pizzorno J
